Mutations in FLG, the gene‐coding profilaggrin/filaggrin, are associated with putative hay fever in patients with atopic dermatitis

Abstract

We report a significant association between FLG mutations, an important predisposing factor for AD, and hay fever in a cohort of 28 Japanese patients with AD. We also show that IgE and TARC levels, considered as reliable indirect markers of AD, have no association with FLG mutation status.