Abstract
Trifluralin is a widely used herbicide. In this study, the mutagenic effect of trifluralin has been evaluated by using Ames mutagenicity test system. In our experiments, trifluralin is examined for its ability to induce reverse mutations in Salmonella typhmurium TA98 and TA100 strains. Mutagenic response is examined in more detail by testing some parameters such as the presence or absence of rat liver S‐9 fraction, preincubation and different concentrations of S‐9 fraction. NADP and phosphate buffer in S‐9 mix. Trifluralin is found weakly mutagenic on TA98 in all of the parameters in the presence of S‐9. No mutagenic effect is detected on TA100 except the condition in which the concentration of NADP is 8 mM in S‐9 mix.
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