Abstract
A comparison was made of the mutagenicity of AFB, by rat, rabbit, mouse, and monkey liver preparations with that of human liver in the Salmonella/microsome assay using S. typhimurium TA98 as the indicator strain. Equal liver protein concentrations (l.2 mg/plate) were used to determine the number of his+ revertants per nmole of AFB1 induced. These values were for rat, rabbit, mouse, Green monkey and human liver preparations, 573±27, 480±22, 269±8, 233±21 and 36±4, respectively.
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Schedule a callMore From: Internationales Archiv für Gewerbepathologie und Gewerbehygiene
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