Abstract
Several viruses show a very high mutation rate and can rapidly evolve to yield new variants resulting in a novel expression of disease. The virus mutation rate is a significant parameter to understand the evolution and pathogenesis of the viruses, to combat them, and has biomedical implications. At the epidemiological and evolutionary levels, the mutation rate is one of the factors that can define the risk of emergent infectious disease. In the wake of the recent novel virus pandemic COVID-19, we review the viral mutation rates, virus dynamics, and various vaccination strategies.
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