Abstract
Summary The tuberculostatic agent isoniazid (INH) was checked for mutagenicity in two mammalian test systems, in the host-mediated assay and the dominant lethal ystem. It could be demonstrated that isoniazid was mutagenic in the host-mediated assay, but in the dominant lethal test a mutagenic activity could not be ascertained. Furthermore, hydrazine proved to be mutagenic in the lost-mediated assay.
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Schedule a callMore From: Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis
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