Mussel-inspired chitin nanofiber adherable hydrogel sensor with interpenetrating network and great fatigue resistance for motion and acoustics monitoring

Abstract

A method for grafting dopamine onto TEMPO-oxidized chitin nanofibers (TOChN) was developed, achieving a surface grafting rate of 54 % through the EDC/NHS reaction. This process resulted in the formation of dopamine-grafted TOChN (TOChN-DA). Subsequently, an adherent, highly sensitive, fatigue-resistant conductive PAM/TOChN-PDA/Fe3+ (PTPF) hydrogel was successfully synthesized based on the composition of polyacrylamide (PAM) and TOChN-DA, which exhibited good cell compatibility, a tensile strength of 89.42 kPa, and a high adhesion strength of 62.56 kPa with 1.2 wt% TOChN-DA. Notably, the PTPF hydrogel showed stable adherence to various surfaces, such as rubber, copper, and human skin. Specifically, the addition of FeCl3 contributed to a multifunctional design in the PTPF interpenetrating network (IPN) hydrogel, endowing it with conductivity, cohesion, and antioxidant properties, which facilitated sensitive motion and acoustics monitoring. Moreover, the PTPF hydrogel demonstrated exceptional fatigue resistance and sensing stability, maintaining performance at 50 % strain over 1000 cycles. These attributes render the PTPF hydrogel a promising candidate for advanced biosensors in medical and athletic applications.