Abstract

A spontaneously occurring myopathy that resembles in many ways muscular dystrophy in man has been observed in a strain of white Pekin ducks. 1,2 Of these ducks, 10% developed contractures, usually between the 7th and 21st day of life, in one or both extremities. 3 Many had muscular weakness and morphologic changes in the muscle without contractures. The histologic lesions in the striated muscle were characterized by focal areas of necrosis within individual muscle fibers. 1-3 Genetic studies now in progress would suggest that transmittal does occur. A variety of agents have produced degenerative lesions in the striated muscle of different laboratory animals: irradiation, 4,5 a chemical, 6 bacterial infections, 7 viruses, 8 vitamin deficiency, 9 and massive doses of cortisone. 10,11 A genetic disease has been described in which there are degenerative lesions in the striated muscle of the mouse, 12 hamster, 13,14 and chicken. 15-17 Progressive muscular dystrophy

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