Abstract

Muscle manifestations and CK levels in COVID infection: Results of a large cohort of patients inside a pandemic COVID-19 area

Highlights

  • Background and aimsObjective to investigate both muscular manifestations and CK levels in a large cohort of patients with COVID-19 infection and to determine whether hyperckemia is associated with morbidity and mortality

  • Anna De Rosaa, Elena Pinuccia Verrengiab, Ivan Merloc, Federico Reac, Gabriele Sicilianod, Giovanni Corraoc, Alessandro Prelleb, aASST Nord Milano, Unit of Neurology, Milan, Italy, bAO Ospedale Civile di Legnano, ASST Ovest Milanese, Legnano, Italy, Neurology-Stroke Unit, Legnano (MI), Italy, cUniversity of Milano-Bicocca Milan, National Centre For Healthcare Research & Pharmacoepidemiology, Milan, Italy, dUniversity of Pisa, Neurology Unit, Pisa, Italy

  • Patients were descriptively analyzed with respect to the following variables: sex, age, muscular manifestations, fatigue, respiratory involvement (SARS pneumonia or respiratory failure) and history of falls

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Summary

Introduction

Muscle manifestations and CK levels in COVID infection: Results of a large cohort of patients inside a pandemic COVID-19 area Background and aims Objective to investigate both muscular manifestations and CK levels in a large cohort of patients with COVID-19 infection and to determine whether hyperckemia is associated with morbidity and mortality. Data of 615 patients discharged from ASST Ovest Milanese (Milan, Lombardy, Italy) with final diagnosis of COVID-19 infection were retrospectively extracted from electronical medical records from 21 February to 1 May 2020. Patients were descriptively analyzed with respect to the following variables: sex, age, muscular manifestations (myalgia and/or arthralgia), fatigue, respiratory involvement (SARS pneumonia or respiratory failure) and history of falls.

Results
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