Abstract
All living organisms and many of their parts are organised in an essentially similar manner: they are closed cavitary bodies. This organisation allows living bodies to change shape by employing hydrostatic forces. It was recently shown that the hydrostatic mechanism lies in the basis of very different morphogenetic processes, and in the basis of muscle contraction (Borkhvardt, 2017). The new hypothesis on the mechanism of muscle contraction explained many issues, but lacked direct proof. Now it seems that such proof has been found.
Highlights
Muscle force is calculated per unit area of this section, e.g., kgf/cm2. This fact disproves the concept of molecular motors and with it the entire modern theory of muscle contraction
I say “strangely enough” because it was the hydrostatic model that I followed in my studies: the new hypothesis of muscle contraction (Borkhvardt, 2009) assumed that it occurred under the impact of external pressure
Taking up and taking out substances — first of all, water — a cavitary body changes the volume of the inner mass, in this way creating and regulating the difference between the internal and the external hydrostatic pressure
Summary
Contraction results from interaction of actin and myosin filaments. Myosin heads turn and pull actin filaments towards the middle of the sarcomere. Smooth muscle cells do not possess a sarcomere organisation at all, and how they contract remains a mystery.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
