Abstract
Background:No analytic epidemiological study has examined the relationship between use of muscle-building supplements (MBSs) and testicular germ cell cancer (TGCC) risk.Methods:We conducted a population-based case–control study including 356 TGCC cases and 513 controls from Connecticut and Massachusetts.Results:The odds ratio (OR) for ever use of MBSs in relation to risk of TGCC was significantly elevated (OR=1.65, 95% confidence interval (CI): 1.11–2.46). The associations were significantly stronger among early users, men with more types of MBSs used, and longer periods of use.Conclusions:MBS use is a potentially modifiable risk factor that may be associated with TGCC.
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