Abstract
Central Nervous System (CNS) disruption of cholinergic (Ach) signaling, which plays a major role in cognitive processes, is well documented in Dementia with Lewy Bodies (DLB) and Alzheimer’s disease (AD) (1,2). The expression of muscarinic Ach receptors type 1 and 4 (CHRM1 and CHRM14) have been reported to be altered in the brain of DLB patients (3). The aim of the present study was to assess the peripheral expression of CHRM1 and CHRM4 in DLB as compared to AD subjects.
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