Abstract

To investigate rickettsioses and leptospirosis among urban residents of Semarang, Indonesia, we tested the blood of 137 patients with fever. Evidence of Rickettsia typhi, the agent of murine typhus, was found in 9 patients. Another 9 patients showed inconclusive serologic results. Thirteen patients received a diagnosis of leptospirosis. No dual infections were detected.

Highlights

  • To investigate rickettsioses and leptospirosis among urban residents of Semarang, Indonesia, we tested the blood of 137 patients with fever

  • We report that murine typhus and leptospirosis are important causes of acute undifferentiated fever (AUF) in Semarang, Indonesia

  • A previous study from rural Thailand identified both diseases in 2.8% and 36.9% of AUF cases, respectively [6,7]

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Summary

Introduction

To investigate rickettsioses and leptospirosis among urban residents of Semarang, Indonesia, we tested the blood of 137 patients with fever. Murine typhus and leptospirosis are likely to share routes of transmission in an urban setting where rats are abundant. The clinical features of mild leptospirosis and murine typhus are nonspecific. Patients with murine typhus exhibit fever, headache, and a rash, the latter is often absent.

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Conclusion
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