Abstract
Thirty days after dorsal and median raphé lesions, when the forebrain content of serotonin (5-HT) was approximately 70 per cent below normal values, lesioned rats showed increased frequency and decreased latency for lethal attacks on mice. Additional observations of muricide on Days 2, 5, 8, and 30 after lesions revealed that frequency and latency of killing increased and decreased, respectively, over time. Since the time-course of this muricide paralleled a progressive reduction of forebrain 5-HT, these data suggest that this neurohumor normally participates in mechanisms exerting inhibitory control over mouse killing.
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