Mural nodule of Anaplastic Carcinoma in an Ovarian Mucinous Cystadenoma- A rare case report

Dr K Subashree,Dr Lavanya M,Dr Maria Maria,Dr C Jayanthi

doi:10.17511/jopm.2020.i04.13

Abstract

Mucinous tumors account approximately for 15% of all primary ovarian epithelial neoplasms. Ovarian mucinous tumors with mural nodules are rare surface epithelial-stromal tumorswhich can be of three types, “sarcoma-like”, sarcoma or anaplastic carcinoma. Mural nodules of anaplastic carcinoma were first described in 1982 by Prat et al following which approximately fifty cases have been reported to date and in those cases, only one has been associated with benign mucinous tumors. The current case report is from a 50-year-oldpostmenopausal woman who presented to the gynecology outpatient department with complaints of abdominal pain and distension for the past five months. On histopathological examination, a diagnosis of Mucinous cystadenoma with focal atypia and mural nodule of anaplastic carcinoma was made and confirmed with immunohistochemistry.

Highlights

Mucinous tumors account approximately for15% of all primary ovarian epithelial neoplasmsand are only the second most common to serious tumors [1]
They can be classified into benign - mucinous cystadenomas, cystadenofibroma, or adenofibroma with focal low-grade atypia, borderline, and malignant- mucinous adenocarcinoma and cystadenocarcinoma
The mural nodules can be of three types, benign "sarcoma-like"? and malignant sarcomatous nodules or anaplastic carcinomatous nodules [2]

Summary

Introduction

15% of all primary ovarian epithelial neoplasmsand are only the second most common to serious tumors [1]. They can be classified into benign - mucinous cystadenomas, cystadenofibroma, or adenofibroma with focal low-grade atypia, borderline, and malignant- mucinous adenocarcinoma and cystadenocarcinoma. Ovarian mucinous tumors may rarely harbor mural nodules which are classified under surface epithelial-stromaltumors. Malignant sarcomatous nodules or anaplastic carcinomatous nodules [2]. The mural nodules can be of three types, benign "sarcoma-like"? They are known to be more associated with borderline tumors or carcinomas of intestinal-type [3]. Mural nodules of anaplastic carcinoma were first described in 1982 by Pratet al [4] following which only less than

Ethical Approval Yes

Findings

Discussion

Conclusion