Abstract
Many biological processes are set into motion when two molecules bind to each other. These binding events are often monovalent in nature—such as when a single binding site on a ligand sticks to a single binding site on a receptor. And monovalent interactions are often remarkably effective. But if monovalent interactions are good, wouldn't bivalent, trivalent, or higher valency interactions be better? For some biological processes, nature seems to have answered this question in the affirmative. Indeed, some multiple binding interactions between a multivalent ligand and a multivalent receptor are not only just a little better but, in fact, are orders of magnitude better. Multivalency is the simultaneous attachment of two or more binding sites on one biological molecule or organism (such as a protein or virus) to multiple receptor sites on another (such as a cell surface). Scientists have long known that multivalent interactions play an essential role in biological processes. But they have ...
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
