Abstract
Confocal microscopy is a powerful imaging tool to obtain high-contrast images of thin sections within bulk tissue. However, tissue scattering limits its utility to only superficial depths. The use of multimode fibers as ultra-thin endoscopes is promising as a deep-tissue minimally invasive imaging tool. Here, we present a method to perform high signal-to-noise ratio (SNR) virtual confocal microscopy through a multimode fiber, by filtering the backscattered light through multiple coplanar virtual pinholes. The use of multiple pinholes helps generate multi-view perspectives of the object, which can be shift corrected and combined to boost the SNR levels. The improved SNR also allows exploiting the potential of confocal imaging for gain in resolution.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
