Abstract
Recently several histologic subtypes of differentiated thyroid carcinomas have been proposed for estimating prognosis of thyroid cancer patients. In this study, therefore, we re-examined 222 patients with papillary carcinoma and 17 with follicular carcinoma especially from the standpoint of clinicopathologic entity of poorly differentiated carcinoma, and undertook the univariate and multivariate analyses for evaluating whether it is of value in estimating survival or disease-free-survival of thyroid cancer patients. As a result, the univariate study showed no difference between papillary and follicular carcinomas, but it showed a significant difference between well and poorly differentiated thyroid carcinomas in survival or disease-free-survival. In the multivariate study, however, the presence of poorly differentiated thyroid carcinoma did not appear as an unfavorable prognostic factor. On the other hand, sex, tumor size and presence of distant metastases and grossly malignant residue in the neck after operation were confirmed as important prognostic factors in the univariate and multivariate studies. These results suggest that the histologic subtyping of differentiated thyroid carcinoma is not necessarily available for estimating the prognosis.
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Schedule a callMore From: The journal of the Japanese Practical Surgeon Society
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