Abstract
Objective: To evaluate the relationship between clinicopathologic features and prognosis of colorectal cancer after surgical treatment.Methods: The relationship between clinicopathological characteristics and prognosis of 941 patients with colorectal cancer after surgical treatment were investigated by univariate and multivariate analysis.Results: The overall 3- and 5-year survival rates of patients with colorectal cancer after surgical treatment were 63.2% and 60.8% respectively with a median survival of 1841 days. Univariate analysis revealed that such factors as gross findings, degree of differentiation, depth of infiltration, nodal and distant metastasis and neoplastic intestinal obstruction were correlated with the survival rate. Dukes stages, gross tumor configuration, intramural spread and differentiation degree were shown to be available independent prognostic factors by multivariate analysis.Conclusion: Dukes stage, as the most important available independent prognostic factor for colorectal cancer (P<0.0005), can be used to assess the postoperative survival.
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