Abstract

Many fields of study still face the challenges inherent to the analysis of complex multidimensional datasets, such as the field of computational biology, whose research of infectious diseases must contend with large protein-protein interaction networks with thousands of genes that vary in expression values over time. In this paper, we explore the visualization of multivariate data through CroP, a data visualization tool with a coordinated multiple views framework where users can adapt the workspace to different problems through flexible panels. In particular, we focus on the visualization of relational and temporal data, the latter being represented through layouts that distort timelines to represent the fluctuations of values across complex datasets, creating visualizations that highlight significant events and patterns. Moreover, CroP provides various layouts and functionalities to not only highlight relationships between different variables, but also dig-down into discovered patterns in order to better understand their sources and their effects. These methods are demonstrated through multiple experiments with diverse multivariate datasets, with a focus on gene expression time-series datasets. In addition to a discussion of our results, we also validate CroP through model and interface tests performed with participants from both the fields of information visualization and computational biology.

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