Abstract
Two-coupled excitatory neurons model containing both calcium-activated non-specific cationic and persistent sodium current in the pre-Botzinger complex (pre-BotC) is studied. A new type of mixed burst similar to a depolarization block bursting (DB-bursting) is observed in the model of pre-BotC neurons. The multi-time scale dynamics, one- and two-parameter bifurcation analysis, are used to study the types of mixed burst and their transition mechanisms. The results show that the periodic fluctuation of calcium concentration has a great influence on the generation of mixed bursting. The change of time scale caused by fluctuation of calcium concentration and the relative position of bifurcation curves have great influence on patterns of bursting.
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