Abstract

Segmenting brain tumors accurately and reliably is an essential part of cancer diagnosis and treatment planning. Brain tumor segmentation of glioma patients is a challenging task because of the wide variety of tumor sizes, shapes, positions, scanning modalities, and scanner’s acquisition protocols. Many convolutional neural network (CNN) based methods have been proposed to solve the problem of brain tumor segmentation and achieved great success. However, most previous studies do not fully take into account multiscale tumors and often fail to segment small tumors, which may have a significant impact on finding early-stage cancers. This paper deals with the brain tumor segmentation of any sizes, but specially focuses on accurately identifying small tumors, thereby increasing the performance of the brain tumor segmentation of overall sizes. Instead of using heavyweight networks with multi-resolution or multiple kernel sizes, we propose a novel approach for better segmentation of small tumors by dilated convolution and multi-task learning. Dilated convolution is used for multiscale feature extraction, however it does not work well with very small tumor segmentation. For dealing with small-sized tumors, we try multi-task learning, where an auxiliary task of feature reconstruction is used to retain the features of small tumors. The experiment shows the effectiveness of segmenting small tumors with the proposed method. This paper contributes to the detection and segmentation of small tumors, which have seldom been considered before and the new development of hierarchical analysis using multi-task learning.

Highlights

  • Among cancers originally from the brain, glioma is one of the most common frequent [1].Glioma arises from glial cells and can be separated into low-grade glioma and high-grade glioma.The high-grade gliomas are malignant and they often have a mean survival time of 15 months [2].Low-grade gliomas may be malignant or benign

  • We propose a network that focuses on small-sized tumors in the brain tumor segmentation problem

  • We evaluated the effectiveness of the proposed model with other models on small-sized tumors

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Summary

Introduction

Low-grade gliomas may be malignant or benign. They develop slowly and can be progressed to high-grade gliomas. Computed tomography (CT), Positron emission tomography (PET), and magnetic resonance imaging (MRI) are the most common ways of detecting and monitoring tumors. Among these ways, MRI is the first chosen method because it has a high resolution, superior contrast, and no harm to patients’ health. In the conventional method of clinical diagnosis and treatment, the doctor needs to navigate 3D images search and segment tumor areas manually, which is very boring, time-consuming, and requires high expertise.

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