Multispectral plasmonic biosensors based on a Penta-supercell metamaterial for detection of prostate-specific antigen: Ultrasensitive in LC resonance mode

Abstract

Here, the detection of prostate-specific antigen (PSA) was done using a refractive index sensor based on a plasmonic Penta-supercells metamaterial array. The proposed Penta-supercells metamaterial array consists of four split ring-shaped supercells and a multiplication-shaped supercell in the middle. The results were validated using the three-dimensional Finite-difference time-domain (FDTD) numerical method. The detection of low-concentration biomolecules is a typical drawback of conventional plasmonic biosensors. Our designed Penta-supercells shape biosensor benefits from an ultra-sensitivity. In our designed biosensor, simultaneous excitations of three main plasmon (inductance–capacitance (LC), quadrupole, and dipole) modes can occur, and the LC mode shows a superior sensitivity. The structure was designed optimally, and three different types of metals (Au, Ag, and Al) were examined. LC mode appeiers in Ag and Au and this mode is not seen in Al. Also, the results of this study show the superiority of Ag to Au and Al. Based on the results of this study, the proposed structure achieves a record high sensitivity of 2256 nm/RIU in LC mode and high sensitivity of 1022 nm/RIU in quadrupole mode, and 494 nm/RIU in dipole mode. As another result, the proposed structure is insensitive to orthogonal polarization. The full utilization of these three resonance plasmon modes shows bright prospects for multi-spectral application. In the case of biosensor application, the designed Penta-supercells-based biosensor and its ultra-high sensitivity of 2256 nm/RIU (4.5 times larger than the sensitivity of conventional plasmonic structures) can help the medical to detect low concentrations.