Year-end Sale % OFF 
Abstract
A novel multi-residue method was developed for the simultaneous analysis of tetracyclines and β-receptor agonists in chicken by coupling pressurized liquid extraction (PLE) with ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS). The parameters of PLE method was optimised, such as extraction solvents, extraction temperature and several other parameters. The performance of the method was assessed and compared to QuEChERS extraction and ultrasound assisted extraction, which were widely used for the chicken extraction. PLE method proved to be suitable for the determination of tetracycline and β-receptor agonists, showing high recoveries, in the range of 84.1–107.9% with relative standard deviation less than 20%. PLE provided low LODs for CHL, OX and TE which were 18.0, 42.0 and 54.0 ng/kg respectively. Additionally, matrix effect of the PLE method exhibited slight effect on all target drugs. However, both ultrasound assisted extraction and QuEChERS extraction exhibited low recoveries and high LODs. The results showed that the established PLE method could be applied to the multiresidue analysis of tetracyclines and β-receptor agonists in chicken to ensure the safety of our daily food supply.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
