Abstract
Solution-state 2D correlation experiments increase signal-to-noise, provide improved resolution, and inform about molecular connectivity. NMR experiments are compromised when the nuclei have broad chemical shift ranges that exceed the bandwidth of the experiment. Spectra acquired under these conditions are unphasable and artifact-prone, and peaks may disappear from the spectrum altogether. Existing remedies provide usable spectra only in specific experimental contexts. Here, we introduce a general broadband strategy that leads to a library of high performing NMR experiments. We achieve arbitrary and independent evolution of NMR interactions by only changing delays in our pulse block, letting the block replace inversion elements in any NMR experiment. The experiments improve the experimental bandwidth for both nuclei by an order of magnitude over conventional sequences, covering chemical shift ranges of most molecules, even at ultrahigh field. This library enables robust spectroscopy of molecules such as perfluorinated oils (19F{13C}) and fluorophosphorous compounds in battery electrolytes (19F{31P}).
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.