Abstract

Oral immunotherapy (OIT) can desensitize food allergic individuals to offending food allergens. However, OIT-induced changes in tissue-resident immune cell subsets remain largely unexplored. We investigated peanut-OIT-induced spatial and temporal changes in gastrointestinal (GI) tract biopsies taken from our phase 2 peanut OIT trial- POISED using Multiplexed Ion Beam Imaging (MIBI).

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