Abstract
In the present study, aberration, body weight, food consumption, haematology, organ coefficients, and both gross and microscopic appearance of some histiocytes were compared between the test and control groups. A sperm abnormality test, bone marrow cell micronucleus test, and a haematology study were conducted at levels of 1.25g/kg, 2.5g/kg, and 5g/kg of trehalose. In both the sperm abnormality test and bone marrow cell micronucleus test, statistically significant differences were observed between the positive control and treatment groups (P<0.05), while no statistical difference was observed among the negative control, high dose, moderate dose and low dose groups (P>0.05). In the haematology study, there was no significant difference found from the controls at P>0.05. The results obtained in the present study could support the conclusion that consumption of trehalose has no adverse effects for humans.
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