Abstract
This study presents a nonlinear system of delay differential equations to model the concentrations of five hormones important for regulation and maintenance of the menstrual cycle. Linear model components for the ovaries and pituitary were previously analyzed and reported separately. Results for the integrated model are now presented here. This model predicts serum levels of ovarian and pituitary hormones which agree with data in the literature for normally cycling women. In addition, the model indicates the existence and stability of an abnormal cycle. Hence, the model may be used to simulate the effects of external hormone therapies on abnormally cycling women as well as the effects of exogenous compounds on normally cycling women. Such simulations may be helpful in understanding the role of xenobiotics in fertility problems, in predicting successful hormone therapies, and for testing hormonal methods of birth control.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
