Abstract
The incidence of multiple primary tumors confined to the oral cavity is 1.4%, more often affecting women without smoking habits. A 67-year-old woman presented with a painful tongue lesion that had not healed for 4 months. She denied smoking and alcoholism. An intraoral examination showed an ulcer with raised borders measuring 2 × 2 cm on the tongue's right border, reddish gingiva with white irregular plaques between teeth 46 and 47, whitish striations with reddish background on the right buccal mucosa, and a 0.5 cm reddish area on anterior lower gingiva. The main diagnostic hypothesis was squamous cell carcinoma; incisional biopsies were performed in all lesions. The histopathological examination confirmed the diagnosis, except on the anterior gingiva with moderate epithelial dysplasia. The patient was referred to the head and neck department for surgical treatment. The possibility of multiple, simultaneous primary oral squamous cell carcinomas should be considered, even in patients without risk factors.
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