Abstract
In 2012, substantial progress has been made in multiple sclerosis research. Simplified diagnostic criteria, which were published in 2011, encompass clinical and imaging features in both adults and children presenting with clinical symptoms suggestive of a first episode of multiple sclerosis.1 In 2012, application of these criteria in a large cohort of children with acute demyelination has shown that the criteria have a high sensitivity and specificity for children older than 11 years with non-acute disseminated encephalomyelitis,2 whereas caution is still needed in the application of these criteria in younger children and in the context of acute disseminated encephalomyelitis-like presentations.
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