Multiple primary cancers in a patient and CT scan features of inferior vena cava leiomyosarcoma: A case report

Abstract

Introduction: Primary inferior vena cava (IVC) sarcoma is a rare tumor of mesenchymal origin arising from the tunica media of inferior vena cava. It accounts for about 0.5% of all soft tissue sarcomas and there are less than 300 cases reported in literature [1, 2]. It is the most common vascular sarcoma [3]. To the best of our knowledge, it has not been reported in combination with any other primary malignancy. Case Report: An 86-year-old female with breast cancer presented with progressive development of bilateral lower limbs edema which was attributed to a palpable abdominal mass. Computed tomography scan revealed a large mass in her inferior vena cava (IVC) with features consistent with an IVC sarcoma. On PET scan, there was moderate grade heterogeneous activity related to the IVC mass, again suggestive of IVC sarcoma. Also, there was an intense uptake at gastroesophageal junction which was proven to be esophageal carcinoma on histology. Patient did not consent for biopsy of IVC lesion due to the risk involved in the procedure hence treated