Multiple-output chemical shift imaging (MOCSI): a practical technique for rapid spectroscopic imaging.

Abstract

A new technique for rapid multiple-frame chemical shift imaging and localized spectroscopy is reported. Unlike phase-encoding techniques and multiple-delay chemical shift imaging techniques, this technique permits spectroscopic imaging at high spatial resolution and moderately high spectral resolution with acquisition times as short as 10 min or less. Unlike other rapid spectroscopic imaging techniques which have been reported, it uses cyclic trapezoidal gradient waveforms achievable in standard clinical magnetic resonance imaging systems. Multiple-output chemical shift imaging images and spectra from a human study are shown.