Multiple Myeloma Presenting as Exophthalmos and Unilateral Central Retinal Vein Occlusion: A Case Report

Abstract

Purpose: To report a case of multiple myeloma presenting with exophthalmos and central retinal vein occlusion. [Editor: The deleted text immediately to the right was not deleted by me.] syndrome associated with retinitis pigmentosa Method: A case report Results: An 88-year-old female patient complained of fullness sensation on in her right eye for several weeks. Three months before ocular presentation, lower back pain with mild numbness radiatinged to the bilateral lower legs was noted. Exophthalmometry revealed 18-mm and 9-mm in the right and left eye respectively. Magnetic resonance image demonstrated a mass lesion about 3×3.8 cm over the superior-lateral quadrant of the right orbit. Multiple myeloma of the right orbit was diagnosed after orbital tumor biopsy, systemic survey and bone marrow aspiration. After radiotherapy for 5 months, the orbital tumor size decreased but central retinal vein occlusion of the left eye was noted. The patient expired due tofrom Streptococcus pneumonia one week later. Conclusion: Ophthalmic presentations of multiple myeloma are rare and the incidence of multiple myeloma as an orbital tumor had beenis reported to be below 1%. Older patients presents with exophthalmos, with symptoms such as generalized fatigue, weight loss or bone pain on movement, the differential diagnosis of multiple myeloma should be included.