Abstract
15Nov 2019 MULTIPLE MYELOMA ONCOGENE - 1 (MUM - 1) DETECTION BY FLOW CYTOMETRY TECHNIQUE IN SOME B - CELL MALIGNANCIES Karima A. Mahfoz , Ashraf A. Sayed , Ahmed M. Moharam Department of Clinical Pathology, Faculty of Medicine, Al-Azhar University.
Highlights
Multiple Myeloma Oncogene 1 (MUM1)/ interferon regulatory factor 4 (IRF4) is a member of the interferon regulatory factor family of transcription factors
Center reaction as well as plasma cell generation. This retrospective study aimed to assess MUM1/ IRF4 diagnostic value as a step for further studies to determine its significance in therapeutic strategies for
MUM1/IRF4 had a significant role as a diagnostic marker in multiple myeloma
Summary
Multiple Myeloma Oncogene 1 (MUM1)/ interferon regulatory factor 4 (IRF4) is a member of the interferon regulatory factor family of transcription factors. Results: MUM1/IRF4 showed highest statistical difference among multiple myeloma group than among Chronic Lymphocytic Leukemia group and least among Non-Hodgkin Lymphoma and control groups. Conclusion: MUM1/IRF4 had a significant role as a diagnostic marker in multiple myeloma.
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