Abstract

The incidence of Multiple Myeloma (MM) following other malignancies is extremely rare. To our knowledge, only 23 cases of this condition have been reported. This study is the first to report on an incidence of MM following bladder cancer after treatment with intravesical Pharmorubicin RD instillation in a 71-year-old male patient. The etiopathology of this specific condition is discussed with an emphasis on two pathogenic features, namely, anthracyclines and gene mutation, which may have been involved in MM development. Regimen consisting of bortezomib may be used as a clinical basis for future treatment of MM following other malignancies.

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