Abstract

Current management options for obese patients include lifestyle changes, pharmacologic and behavioral therapies, and bariatric surgery. Although surgery is the only treatment that can provide a dramatic, lasting weight loss in these patients, it is associated with a significant morbidity. The obesity epidemic mostly concerns relatively less obese patients (i.e., body mass index [BMI] 30–35 kg/m2), with or without co-morbidity, who do not meet the current weight criteria for surgical therapy. Because of this, there has been a drive toward less invasive, endoscopic, potentially ambulatory procedures that mimic current mainstream bariatric procedures but with limited associated morbidity.

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