Multiple forms of dipeptidases in normal human intestinal mucosa and in mucosa from children with coeliac disease

Abstract

Dipeptidases and tripeptidases from normal human intestinal mucosa and from mucosa of patients with coeliac disease were compared by starch gel electrophoresis. The number of major peptidase bands was identical in both types of mucosa, although the intensity of some peptidase bands was weaker in coeliac mucosa, especially when leucyl proline was the substrate.