Abstract

Acute pancreatitis (AP) is an acute inflammatory process of the pancreas with variable clinical presentations. Splanchnic venous thrombosis is a well-known vascular complication of AP and commonly present as thrombosis of the splanchnic venous system: splenic vein (SplV), portal vein (PV) and superior mesenteric vein (SMV), either separately or in combinations. Involvement of extra-splanchnic vessels is rare and associated with morbidity and mortality. Vascular complications are late phenomena and usually associated with local complications of AP, namely acute fluid collections, necrotizing pancreatitis and walled-off pancreatic necrosis. Pathogenesis of venous thrombosis is multifactorial in which pancreatic inflammation and systemic inflammatory response play a key role. At present, there are no consensus guidelines on treatment and use of anticoagulation for venous thrombosis in the setting of AP. Limited literature suggests the use of anticoagulation in presence of PV with or without SMV thrombosis and extrasplanchnic vessel involvement. Literature on extra-splanchnic vessels involvement in acute pancreatitis is sparse. Here we present two cases with multiple extra-splanchnic vessels involvement and their management.

Highlights

  • Acute pancreatitis (AP) is an acute inflammatory process of the pancreas with variable clinical presentations

  • We further evaluated the patient with blood investigations and contrast enhanced computed tomography scan (CECT) of abdomen and chest

  • Complications are well known in AP and commonly present as thrombosis of the protein C and S, antithrombin III, factor V Leiden, JAK 2 mutation, homocysteine and

Read more

Summary

Introduction

Acute pancreatitis (AP) is an acute inflammatory process of the pancreas with variable clinical presentations. Patient without SMV thrombosis and extra- ing about 8.4×4.2×5.2 cm which extended improved symptomatically and was dissplanchnic vessel involvement. Literature on extra-splanchnic vessels involvement in acute pancreatitis is sparse.

Results
Conclusion

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.