Multiple evanescent white dot syndrome

Abstract

Multiple evanescent white dot syndrome (MEWDS) was described by Jampol et al. in 1984 in 11 young patients who had unilateral transient retinal pigment epithelium (RPE) granularity and white dots at the level of RPE with vitreous cells[1]. It is predominantly a disease of the photoreceptors with occasional involvement of the outer nuclear layer. Inflammatory microglial activation and changes in deeper retinal circulation contribute to the features of MEWDS[2]. Patients are usually young females and may have a preceding history of flu-like illness. This reversible condition involves the photoreceptors causing reduced amplitudes in the full field and multifocal electroretinogram (mfERG), which recovers with the resolution of the disease[3]. We present a case of MEWDS in a young female with typical clinical features with spontaneous improvement in symptoms with observation.