Abstract

We have recently encountered a case of multiple eosinophilic granulomas in the fornix of the stomach. A 51-year-old woman was admitted to our hospital with a chief complaint of epigastralgia. Radiologic and endoscopic examinations showed irregular, excavated and protruded lesions in the fornix. Endoscopic biopsy showed benign findings (Group-I). With a suspicion of gastic malignant lymphoma or reactive lymphoreticular hyperplasia (RLH), total gastrectomy was performed. The resected specimen showed five protruding lesions of various sizes (maximum 1.6×1.3cm, minimum 0.6×0.6cm) with an ulcer at the top of each. Histologic diagnosis was eosinophilic granuloma of the stomach. One hundred and thirty-three cases of eosinophilic granuloma of the stomach have been reported in the Japanese literature. We discussed the age distribution, sex difference, symptoms, location, size, shape, layer of occurrence, preoperative diagnosis, and treatment of this lesion in the light of these reports.

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