Abstract
A fifty seven year-old male patient with mantle cell lymphoma (MCL) firstly diagnosed four years ago. After first chemo-radiotherapy the disease was in remission for two years. He was admitted with persistent dry cough and his computed tomography revealed left upper lobe atelectasis due to endobronchial tumoral involvement and narrowed right lower lobe bronchus surrounded by soft tissue density. Bronchoscopy revealed an endobronchial tumoral lesion obstructing left upper lobe bronchus, and three submucosal nodules located in right upper lobe, intermediate and middle lobe bronchi. The lesions were sampled by endobronchial cryobiopsy and histopathological and immunochemical investigation revealed mantle cell lymohoma infiltration. Endobronchial involvement of non-Hodgkin9s lymphomas (NHL), especially MCL is a very rare entity. To the best of our knowledge, this is the third case with endobrobchial involvement of MCL in the current literature. In any case of NHL with dry cough, wheeze or radiological atelectasis, endobronchial involvement should be born in mind and pathological confirmation is essential. Cryobiopsy is a safe method which is also more diagnostic yield, to sample such lesions.
Published Version
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