Abstract

The multiple drug hypersensitivity is an rare syndrome, severe as presentation, evolution and therapeutic approach as well as for the patient, as for the allergist. It includes a panoramic approach of the clinical already assessed reactions (severe general urticaria, laryngeal edema, Quincke edema, anaphylaxis).

Highlights

  • A case report of an 50 years old patient which started 14 years ago, with an severe onset – glotic edema with anaphylaxis, after a second intake of Rocephin (Sodium Ceftriaxone) and due to an emotional distress and associated with a malfunction of the thyroid status. He develops within a 3 year period of time a multiple drug hypersensitivity syndrome to beta lactam and non beta lactam antibiotics, inhibitors of converting enzyme, thiopental and COX2 inhibitors

  • The thyroid status and pshycological type of reaction- as strong choleric, large catecholamines amount releaser recommends him for a detailed test for Ig E, non Ig E, mast cell degranulation test or lymphoblastic transformation test

  • It is quite improbable that an overview for all drugs for specific Ig E could be performed in terms of financial expenditure

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Summary

Celina Stafie

From 6th Drug Hypersensitivity Meeting (DHM 6) Bern, Switzerland. 9-12 April 2014. The multiple drug hypersensitivity is an rare syndrome, severe as presentation, evolution and therapeutic approach as well as for the patient, as for the allergist. From 6th Drug Hypersensitivity Meeting (DHM 6) Bern, Switzerland. The multiple drug hypersensitivity is an rare syndrome, severe as presentation, evolution and therapeutic approach as well as for the patient, as for the allergist. It includes a panoramic approach of the clinical already assessed reactions (severe general urticaria, laryngeal edema, Quincke edema, anaphylaxis)

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