Abstract

<h3>To the Editor:—</h3> Regarding "Multiple Cases of Leukemia Associated with One House" as reported by McPhedran and Heath (<b>209</b>:2021, 1969), I would like to suggest that a study of the mold population of the house be made. Mycotoxin produced by a species of<i>Fusarium</i>and possibly other genera were responsible for "toxic alimentary aleukia" and resulting death in humans in Russia in 1944 after the victims ate bread prepared from infested grain which had wintered in the field. The disease is characterized by agranulocytosis, necrotic and hemorrhagic skin lesions, and hemorrhages particularly of the intestinal tract.<sup>1</sup>This is one of the few instances of disease in man traced directly to mycotoxins, but it is well known that mycotoxins are responsible for certain diseases in animals (ie, facial eczema in sheep and cattle, stachybotryotoxicosis in horses, hemorrhagic disease in poultry, aspergillus toxicosis in cattle, moldy corn toxicosis in swine.

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