Abstract

Recent newly developed ultrasound (US) techniques extend our ability to study the cerebral hemodynamics in patients with arteriovenous malformations (AVM) beyond the conventional cerebral blood flow velocity ( CBFV) analysis. We present US data of global cerebral blood flow ( CBF) and global cerebral circulation time ( CCT) in a patient with a unique bihemispherial diffuse cerebral angiomatosis and compare them with 10 age-matched controls. In addition, the estimation of an US-derived global cerebral blood volume ( CBV) is proposed. Duplex sonographic CBF analysis revealed 2620 mL/min in the patient and 754 ± 93 mL/min in controls. Doppler sonographic CCT was 2.9 s and 6.3 ± 1.5 s and CBV 126 mL and 79 ± 19 mL, respectively. US allows a simple, minimal invasive bedside analysis of several global hemodynamic parameters that might provide valuable additional information in patients with diffusely altered cerebral hemodynamics. (E-mail: Stephan.Schreiber@charite.de)

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