Abstract

Metastatic testicular germ cell tumors patients require histology- and stage-appropriate therapy to achieve optimal therapeutic outcomes. This work focuses on the interdisciplinary presentation of current recommendations for the treatment of metastatic germ cell tumor patients. The interdisciplinary recommendations were formulated based on the German S3guideline and supplemented by recent literature. Using astage-specific and guideline-based treatment approach, interdisciplinary cooperation between urology, oncology, and radiotherapy is mandatory to successfully achieve ahigh rate of cure and, in the case of complex advanced tumors, also the most effective therapy possible. The question of optimal treatment approaches for seminoma in cSIIA/B remains particularly challenging. Since treatment of advanced or multiple relapsed germ cell tumor patients remains complex, patients should be referred for an online second opinion ( https://urologie.ekonsil.org ).

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