Multimodal analysis based on high‐field magnetic resonance and motor evoked potentials: A case report of multiple sclerosis

Abstract

AbstractBackgroundMagnetic resonance imaging is widely used in the evaluation of multiple sclerosis (MS). Diffusion tensor imaging can provide information about structural changes in MS that is inaccessible with other magnetic resonance imaging techniques.Case presentationWe describe the case of a 13‐year‐old girl presenting with muscle weakness in the right lower limb related to a relapse of MS. The patient underwent full tensor imaging with a high‐field magnetic resonance imaging unit and motor evoked potential recording at the phases of relapse and remission. In the diffusion tensor tractography, tracing the left pyramidal tract fiber bundles was improved at relapse compared with at remission. Central motor conduction times and latency were normal at both relapse and remission, but amplitude levels for cortical motor stimulation were higher during remission than relapse. The findings of diffusion tensor imaging reflected the motor evoked potentials results and clinical course.ConclusionsWe tested a new technique that provides visualization of the pyramidal tracts in a patient with MS. Tractography was shown to be a clinically feasible technique that correlates well with clinical symptoms and motor evoked potentials.