Abstract
Bone tissue engineering strategies face considerable challenges owing to the complexity of the bone. This study introduces an unconventional method based on multimaterial 3D coextrusion-(bio)printing to address some of these challenges. The strategy enables simultaneous (bio)printing of a poly(lactic-co-glycolic acid)-based polymer ink laden with hydroxyapatite and a gelatin methacryloyl (GelMA)-based hydrogel bioink containing mesenchymal stem cells (MSCs). The resulting composite scaffolds exhibited a trabecular bone-like porosity and favorable compressive properties, surpassing those of GelMA alone. The (bio)printed MSCs demonstrated favorable viability, proliferation, morphology, and differentiation. This converged approach in multimaterial (bio)printing has the potential to transform the field of bone tissue engineering, offering a more efficient and effective way to regenerate skeletal tissues.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
