Abstract
Multilocus Enzyme Electrophoresis – Application to the Study of Meningococcal Meningitis and Listeriosis
Highlights
An important element of epidemiological investigations of disease outbreaks is the microbiological and genetic characterization of the causative microorganisms
Some of the methods used to characterize outbreaks include plasmid analysis, chromosomal fingerprinting by restriction fragment length polymorphism, polymerase chain reaction, RNA sequencing and multilocus enzyme electrophoresis (MEE)
Several important features conceming the genetic relationships of meningococci and the spread of meningococcal disease have been revealed through major studies which have ex
Summary
An important element of epidemiological investigations of disease outbreaks is the microbiological and genetic characterization of the causative microorganisms. New methodologies based on the detection of markers controlled by stable genetic material have become a major tool for determining clonality among a group of bacterial strains and a Correspondence and reprints: Dr FE Ashton. Since many bacterial enzymes are polymorphic, MEE provides a highly discriminatory method for detection of bacterial clones, which are identified by distinctive electrophoretic enzyme profiles termed 'electrophoretic types'.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
