Abstract
Multilocular cystic renal cell carcinoma (MCRCC), which exhibits low-stage and low-grade characteristics, is a special type of RCC. MCRCC is extremely rare and generally develops at ages >50 years. We herein report a case of MCRCC in a 28-year-old man, which, to the best of our knowledge, is the youngest case reported worldwide to date. The patient presented with irritative bladder symptoms for 1 year. Dynamic enhanced computed tomography (CT) imaging revealed a mass with inhomogeneous enhancement in the left kidney, with a rich blood supply. B-ultrasonography also revealed a renal protruding mass. As the mass was highly suspicious to be a malignant tumor, laparoscopic radical nephrectomy was performed and MCRCC was definitively diagnosed by pathological examination. The patient has been regularly followed up for 6 months, without complications or disease recurrence.
Highlights
Multilocular cystic renal cell carcinoma (MCRCC) was first reported by Perlmann in 1928 and named lymphangiohemangioma [1]
MCRCC has non‐specific symptoms, it is a tumor of low grade, with low malignant potential; it is curable by surgical resection, either simple nephrectomy or nephron‐sparing surgery, and it has a favourable prognosis compared with other types of renal cancer, such as clear‐cell and tubulocystic cancer [2]
We present the case of a 28‐year‐old male patient, who, to the best of our knowledge, is the youngest MCRCC patient reported to date
Summary
Multilocular cystic renal cell carcinoma (MCRCC) was first reported by Perlmann in 1928 and named lymphangiohemangioma [1]. MCRCC consists of multiple cysts containing old and fresh hemorrhagic material, with clear cells in the septa separating the cysts, which may make. Laboratory examination revealed a white blood cell count of 9.59x109/l and a haemoglobin level of 157 g/l. The pathologist observed that the clear tumor cells adhered to the inner wall of the cyst and their nuclei were significantly hyperchromatic (Fig. 2A). The immunohistochemical staining examination (Fig. 2B‐D) revealed that the tumor cells were positive for cytokeratin (CK), CK7 and epithelial membrane antigen. The patient was discharged on the sixth postoperative day and he had a good recovery. He has since been routinely followed up and remains alive without evidence of recurrence
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