Abstract

Biomimetic Structures Annulus fibrosus (AF) repair is critical for treating disc herniation. In article 2200895, Fengxuan Han, Bin Li, and co-workers fabricate aligned core–shell nanofibrous scaffolds mimicking AF microstructure and realize temporal release of drugs for AF repair. Fast release of ibuprofen-ameliorated inflammation and sustained release of TGFβ3 promote cell proliferation and ECM secretion.

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