Multifunctional halloysite nanotube based composite coatings on titanium as metal implant for orthopedic applications

Abstract

The development of orthopedic implant materials which promote osseointegration and reduce bacterial infection has gained considerable attention to avoid long-term complications in the biomedical industry. Present study reports the electrodeposition of strontium-halloysite nanotubes (Sr-Hal)/lanthanum, cerium substituted hydroxyapatite (La,Ce-HAP) composite coatings on titanium surface with varying Sr-Hal concentration at 1, 2 and 3 wt%. Their physicochemical and morphological characterizations were performed. The mechanical properties of the coatings were evaluated using adhesion and microhardness tests and from the obtained results it was found that, the incorporation of Sr-Hal improved the mechanical properties of the composite coatings. The electrochemical assessment of composite coated Ti surfaces in simulated body fluid (SBF) solution was investigated using polarization measurements. The anti-corrosion properties of the Sr-Hal/La,Ce-HAP composite coated Ti with 3 wt% Sr-Hal was found to be excellent compared to the other wt% of Sr-Hal incorporated in the composite. The antibacterial, anti-cancer and cell viability study of Sr-Hal/La,Ce-HAP composite coatings and their results reveal the bactericidal effect, osteosarcoma cell growth impediment and higher number of viable cells respectively. As a whole, all the studies exposed that the Sr-Hal/La,Ce-HAP composite coatings on Ti has improved the mechanical, anticorrosion and biocompatible performance indicating the Sr-Hal/La,Ce-HAP composite coated titanium is a prospective implant material for orthopedic applications.